A lot of people suffer from pain very often or even constantly. Many people take painkillers almost every day, but rarely does anyone choose them correctly for themselves.
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There are many types of pain for which it is not always convenient to go to the doctor. For example, moderate and occasional pain in muscles and joints, headaches, hangovers, regular pain during menstruation in women. But on the other hand, people get confused. They make the wrong choice by buying a medicine that is not at all ideal for them. Some chose it under the influence of advertising, others on the advice of friends. Many people have their own favorite drug, which has relieved them of pain more than once. And they generously recommend it to others. In this case, as a rule, very powerful analgesics are recommended - it’s like shooting sparrows from a cannon. Such excess medications, while relieving pain, also have a harmful effect; they have many more side effects.
Comparison of the effectiveness of Baralgin M and Tempalgin
Tempalgin is more effective than Baralgin M - this means that the ability of the drug substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Tempalgin is more pronounced, then with Baralgin M it is impossible to achieve this effect even in large doses.
Also, the speed of therapy is an indicator of the speed of the therapeutic action; Tempalgin and Baralgin M are also different, as is bioavailability - the amount of the drug reaching the site of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Table: Instructions for assembling medicines
| Preparations from one “part” | Preparations from 2–3 “parts” | Preparations made from more than 3 “parts” | |
| Simple painkillers (ASA, paracetamol, metamizole, ibuprofen, naproxen) | Painkillers + caffeine | Painkillers + antispasmodic | Painkillers + antispasmodic + caffeine + antihistamine |
| Aspirin, upsarin, analgin, Panadol, efferalgan, nurofen | Citramon P, Gevadal, Panadol extra, Solpadein Fast, Citrapar, Benalgin, Acifein, Caffetin sk, etc. | Trigan-D, Unispaz N, Spazmalgon, etc. | Pentalgin, Spazmalgon Effect |
Comparison of safety of Baralgin M and Tempalgin
The safety of a drug includes many factors.
At the same time, in Baralgin M it is quite similar to Tempalgin. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Baralgin M, as well as Tempalgin, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Baralgin M does not have any risks when used, just like Tempalgin.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Baralgin M and Tempalgin.
Composition of the substance
The medicine is a strictly cylindrical tablet, designed with a chamfer and a score for convenient division into equal parts. Analgin tablets are usually dense white, sometimes with yellow splashes and a uniform yellowish tint.
The main active ingredient of the drug is metamizole sodium monohydrate. One tablet contains 500 mg. There are also tablets with a reduced dose of the active substance, equal to 250 mg.
In addition, the medicine contains a number of excipients, for example, potato starch, talc, calcium stearate and sodium lauryl sulfate.
The active components of the drug provide the drug with a pronounced analgesic, antipyretic and anti-inflammatory effect. Absorption of the components occurs in a short time through the gastrointestinal tract. After a certain period of time, it is excreted from the body by the kidneys without causing harm.
Comparison of addiction between Baralgin M and Tempalgin
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “syndrome o” in Baralgin M is quite similar to the similar values in Tempalgin. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Baralgin M the meaning of the “syndrome” is quite small, however, the same as in Tempalgin.
The Fab Five?
Let's take a closer look at the strengths and weaknesses of each of these drugs. There will be no shortage of incriminating evidence against them - competition among painkiller manufacturers is very high and they are constantly at war with each other.
Acetylsalicylic acid. Helps with almost all pains, acting for 3-6 hours. One of the most popular medicines, used for more than 100 years, and one of the most reviled - it can cause gastritis, ulcers and even bleeding from the stomach. How should we feel about this? If you had such complications before, you should not take ASA. Occasional use is unlikely to be aggressive for the stomach. There is no need to take ASA on an empty stomach and do not exceed a single dose of 600–750 mg. ASA is contraindicated for children under 14 years of age: it is believed that it sometimes causes Reye's syndrome in children, a very rare but serious and dangerous disease.
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Ibuprofen. It is gentler on the stomach than ASA. The pain relief time is also slightly longer – 4–8 hours. But ASA is better for the heart; frequent use of ibuprofen by heart patients increased their risk of heart attacks and strokes by almost 2 times. Many of them take low doses of ASA for prevention, and ibuprofen blocked its effect. Therefore, it is better to take it by young people rather than older people.
Naproxen. It is similar to ASA and ibuprofen, and the side effects of these drugs are common. In terms of the degree of aggressiveness to the stomach, it occupies an intermediate position between these drugs. It relieves pain well and lasts longer, so you need to take it 2 times a day, maximum 3 times.
By the way: all these three drugs have a triple effect. They not only relieve pain, but also lower the temperature. In addition, they have an anti-inflammatory effect. Because of the latter effect, they are also used for rheumatic diseases, for which inflammation and pain in the joints are typical. The other two analgesics (metamizole, paracetamol) do not have this effect; they are used only for pain and to reduce high fever.
Metamizole (analgin). They scold the drug no less than ASA, claiming that it is banned almost everywhere due to the fact that it inhibits the formation of white blood cells (agranulocytosis). This is a very strong exaggeration: the drug fell victim to pharmaceutical wars in only a few countries, and it causes this complication in one case in a million. In addition, almost all painkillers and a bunch of other drugs are to blame for this.
Paracetamol. They always say about it that, unlike ASA and ibuprofen, it does not irritate the stomach. This is true, but it is difficult to find another medicine that would be so insidious towards the liver. There are cases when a therapeutic daily dose of paracetamol of 4 g turned out to be fatal for this organ. The drug is especially dangerous for those who already have a diseased liver or who drink moderately (the critical daily dose is 3 small glasses of vodka or 3 glasses of wine). In no case should you relieve a hangover with this medicine, trying to eliminate the headache, and in no case should you exceed the dose. It is better not to take more than 0.5 g at one time. And if paracetamol is taken with other medications, you must definitely check their composition. This substance is so often used in complex preparations that it is easy to overdose.
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Comparison of side effects of Baralgin M and Tempalgin
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Baralgin M has almost the same level of adverse events as Tempalgin. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Baralgin M are similar to Tempalgin: how quickly the body recovers after taking it and whether it recovers at all.
Side effects
It is forbidden to use the drug for severe pain in the stomach, the origin of which has not been identified. Until a proper diagnosis is made, Analgin is not used in therapy. If the dosage and duration of the course of taking the tablets are not observed by the doctor, as well as when taking the drug under existing contraindications, allergic reactions may occur.
Most often, side effects are manifested by a skin rash, quite intense, as well as Quincke's edema. Less commonly observed are Lyell's and Stevens-Johnson syndromes, as well as anaphylactic shock. With long-term use of the drug as an anesthetic, changes occur in the blood formula.
Instructions for use of analgin highlight several side effects:
- risk of developing thrombocytopenia or leukopenia;
- bronchospasm attack;
- a strong decrease in blood pressure;
- malfunctions of the renal system.
When the first signs of deterioration in the patient’s condition appear, it is important to immediately stop taking the drug and report the incident to the treating doctor. To change painkillers, you need to visit a doctor to clarify the need to change the medication.
An overdose of a substance occurs in case of prolonged use of the drug, more than a week in a course in increased dosages, as a pain reliever. This may be manifested by nausea and vomiting, delirium, impaired consciousness, shortness of breath, and a sharp decrease in blood pressure.
If dangerous conditions of the body are determined, you should immediately consult a doctor and stop taking the drug. It is important to perform gastric lavage and also start using saline laxatives. They also increase their drinking regime and follow a diet. In particularly difficult cases, you will have to go to the hospital and undergo a hemodialysis procedure.
Comparison of ease of use of Baralgin M and Tempalgin
This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.
The ease of use of Baralgin M is approximately the same as Tempalgin. However, they are not convenient enough to use.
The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.
Last update date: 2020-12-04 13:44:51
Pregnancy and lactation
Research on the effects on the body of pregnant women taking Analgin has not been carried out to a sufficient extent. As a result of animal studies, no serious disturbances in the functioning of the body were identified.
And yet, the drug can provoke serious perinatal problems, so taking the drug in the first and third trimester is strictly prohibited. The use of a substance in the second trimester occurs with extreme caution, under the supervision of a doctor, and only when the potential benefit to the mother is higher than the well-being of the fetus.
The drug is also not used during breastfeeding, as it easily passes into breast milk and can harm the baby. Feeding is allowed only 48 hours after completion of the drug.
The dosage of analgin for children is also prescribed by the doctor. Self-medication is not allowed in case of pathologies or fever in a child. Even half of a pill taken can have a detrimental effect on the body, so you should first undergo tests and get detailed advice from a qualified doctor. Only a doctor can prescribe medication in accordance with the nature of the disease.
Where to buy, how much it costs
You can buy the drug at almost any pharmacy; it is available without a prescription. At the same time, the price of analgin is affordable for every patient. The cost of a pack of blisters containing 20 tablets of the substance is about 1 ruble.
Analgin is a medicine that was actively used by our grandmothers during the USSR period, when a variety of drugs similar to today’s was not available on the pharmaceutical market. Traditionally, today it is one of the most accessible and inexpensive medicines with a wide range of applications in various pathologies. It is prescribed to adults and children when severe spasms occur. Or taken urgently in case of increased body temperature.
Interaction with other drugs
In the case of simultaneous use of Analgin with cyclosporine, the level of the latter in the blood can be significantly reduced. It is important to inform your doctor about this; you may need to increase the dosage of the drug if you need to take a painkiller.
Severe hyporemia can occur when the substance is combined with chlorpromazine. Elderly patients are at high risk of developing hematological toxicity when used concomitantly with methotrexate.
Analgin should be used with acetylsalicylic acid and bupropion with great caution. The drug interacts and reduces the effectiveness of antihypertensive substances.
