Falimint is a drug that has an antiseptic and local anesthetic effect. Available in the form of dragees for resorption in the oral cavity. The active substance is acetylaminonitropropoxybenzene, which inhibits the proliferation of pathogenic bacteria and eliminates sore throat. Indications for use include infections of the upper respiratory tract (pharyngitis, tonsillitis, laryngitis, tonsillitis) and oral cavity (stomatitis, gingivitis). The drug is prescribed in preparation for an instrumental examination of the pharynx and teeth. Currently, the drug is not commercially available.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The active ingredient Falimint is an aromatic nitro compound.
The effect of the drug is similar to the effect of menthol:
- there is a feeling of pleasant coolness in the mouth and throat;
- no dryness or numbness occurs;
- breathing becomes easier immediately;
- reflex cough stops;
- mucus thins;
- pain is alleviated;
- the inflammatory process decreases;
- if there was a urge to vomit during medical manipulations in the oral cavity, they are suppressed.
Pharmacokinetics
After oral administration, Falimint is quickly absorbed. The maximum concentration of unchanged drug in plasma is achieved after 30-60 minutes.
It is excreted from the body in the form of metabolites in the urine. The maximum concentration of the altered drug in the urine is observed 2 hours after taking the tablets.
This is interesting!
Despite the wide popularity of Falimint all over the world, not a single clinical study of the drug has been conducted. Interestingly, post-marketing observations, based on feedback from doctors and patients, did not reveal any shortcomings of the tablets or clinically significant side effects. This confirms that Falimint is an effective and relatively safe drug. It is logical to assume that discontinuation in Russia is not associated with toxic effects on the body or severe allergic reactions during therapy.
Indications for use
What Falimint tablets help with:
- diseases of the respiratory system, in which a pronounced inflammatory process is observed, in particular, tablets are taken for pharyngitis , laryngitis and tonsillitis ;
- inflammatory processes in the oral cavity, for example, stomatitis or gingivitis ;
- non-productive, dry reflex cough ;
- pronounced gag reflex during medical manipulations in the mouth and pharynx.
In most cases, in the treatment of inflammatory diseases it is used as an adjuvant.
How does it affect the body? (Pharmacodynamics)
The medicine is prescribed when it is necessary to act on the mucous membrane of the oral cavity and upper respiratory tract. As it dissolves, sensations arise similar to those left after menthol candy:
- a feeling of pleasant coolness appears in the mouth, throat;
- dryness, numbness, tickling disappears;
- sore throat becomes less;
- the dry, barking cough that occurs when the upper respiratory tract is irritated or inflamed disappears;
- both oral and nasal breathing are facilitated;
- gagging, which may accompany manipulations in the oral cavity, is suppressed.
The drug simultaneously has an anesthetic, anti-inflammatory and antitussive effect. It accumulates on the surface of the oral mucosa, complementing complex therapy with local action. It is recommended not only as a remedy for the treatment of colds, but also in preparation for all kinds of manipulations in the oral cavity. For example, before making dental impressions or trying on dentures.
There are no absolute contraindications to the use of falimint. If you are intolerant to one or more components that make up the pills, allergic reactions may occur. Doctors recommend using falimint with caution during pregnancy and breastfeeding. Although the active substance does not enter the blood, the effect of acetylaminonitropropoxybenzene on a pregnant woman and fetus has not been thoroughly studied.
Instructions for use of Falimint (Method and dosage)
The tablets should dissolve in the mouth. Take one tablet, no more than 10 tablets per day.
The medicine can only be used for a few days. The duration of the course is individual and should be selected by the attending physician. But if during this time the disease has not gone away, there is no need to extend the course, it is better to choose another drug.
Instructions for the use of Falimint for children have not been developed, since there is not enough information regarding the effectiveness and safety of using the medicine to treat children.
"FALIMINT": composition
- The therapeutic effect is provided by the active substance of the tablets with a complex name: acetylaminonitropropoxybenzene. It is a benzene derivative to which acetyl and nitrate groups were added during synthesis. Its original properties have been changed. Each pellet of the medicine contains 25 mg.
- Additional components are added both to the main substance (to increase the mass of the dragee) and to its shell. Inside the drug contains: sucrose, gelatin, solid fat, talc, copovidone, colloidal silicon dioxide, magnesium stearate. The listed substances, except for copovidone, are intact and do not react with acetylaminonitropropoxybenzene. They are harmless to humans and have no therapeutic effect. Copovidone is part of detoxification drugs and blood substitutes. It helps remove waste products from bacteria from the body, cleanse the blood of antigens, etc.
- The shell of the dragee is made from substances that are more often used by cooks, not pharmacologists. It contains: sucrose, glucose syrup. Liquid and solid paraffin help give the drug a dragee shape. 30% simethicone emulsion was added as an antifoam.
Using the listed components, round white lozenges for resorption with a smooth surface are formed. Packs 20 pieces per package and is recommended to be stored at room temperature.
special instructions
When treating with Falimint, you should adhere to the following recommendations:
- it is necessary to stop taking the medication if signs of a skin allergic reaction appear;
- patients with diabetes should remember that the medicine contains a certain amount of sugar (1 tablet – 0.03 bread units);
- Tablets should not be taken by persons with congenital intolerance to glucose or fructose, with glucose-galactose malabsorption or sucrose-isomaltose deficiency;
- You should not take the medicine for more than a few days.
Why Falimint disappeared from pharmacies
For many years, the drug has been effectively used for throat diseases in children and adults, and has gained well-deserved popularity among doctors and patients. Falimint helped to quickly cope with the infection and make it easier to endure the symptoms of the disease due to the local analgesic effect. However, at the end of 2021, the drug disappeared from pharmacy shelves and has not yet gone on sale.
Initially, Falimint was produced by the German pharmaceutical concern Berlin-Chemie. Then a subsidiary was created in Russia, which began to produce the drug on the domestic market. After Falimint disappeared from pharmacies, there were many theories.
Some of them referred to the economic crisis and the high cost of raw materials supplied from India and China. Others suggested a pharmaceutical conspiracy to create artificial hype around the drug in order to inflate the price. One of the first popular theories pointed to the re-registration of tablets due to a change in composition or dosage form.
When contacting the administration of Berlin-Pharma CJSC, a response was received that Falimint had been discontinued from production in Russia. They refused to announce the reason, citing non-disclosure of trade secrets. Most likely, the license from Russia was revoked as a result of problems with production and violations of the drug’s manufacturing technology. This theory is confirmed by the fact that in other countries Falimint remains on sale to this day.
>>We recommend: if you are interested in effective methods of getting rid of chronic runny nose, pharyngitis, tonsillitis, bronchitis and persistent colds, then be sure to check out this page of the site after reading this article. The information is based on the author’s personal experience and has helped many people, we hope it will help you too. Now let's return to the article.<<
Analogs
Matches by level 4 ATC code:
Suprima-ENT
Ingalipt-N
Strepsils Plus
Strepsils
Ingalipt
TheraFlu LAR
Hexoral Tabs
Lisak
Efizol
Angilex
Kameton
Anzibel
Agisept
Yox
Lugol's solution with glycerin
Lugol
Laripront
Stopangin 2A
Stopangin
Septolete Neo
Analogues of Falimint:
- Agisept;
- Vocasept;
- Hexoral Lorcept;
- Gorpils;
- Gripcold;
- Koldakt Lor Pils;
- Rinza Lorsept;
- Strepsils;
- Suprima-Lor;
- Trisils.
Falimint's analogs
The withdrawal of a drug from production in Russia is an unpleasant event for adherents of the drug. However, this fact should not cause disappointment, especially since you can find a wide variety of effective analogues in the pharmacy chain. All substitute drugs have a different structure, but have a similar therapeutic effect. They can have a simple or complex composition.
Table - Analogues of Falimint
Name | Active substance |
Analogs with one active ingredient | |
Hexasprey | biclotymol |
Stopangin | hexethidine |
Isla Mint and Isla Moos | Icelandic moss extract |
Combined analogues | |
Givalex | hexethidine, chlorobutanol, choline salicylate |
Lysobacter | lysozyme, pyridoxine |
Strepsils | amylmetacresol, dichlorobenzyl alcohol |
Septolete | thymol, eucalyptus and peppermint oil, levomenthol, benzalkonium chloride |
Most analogues have a more affordable price and allow you to reduce the financial costs of treatment.
"FALIMINT": why was it discontinued?
The medicine disappeared from pharmacies at the end of 2021. There have been various versions of why falimint was discontinued: because of the economic crisis, which caused a sharp increase in the dollar exchange rate against the ruble and the cost of raw materials purchased for foreign currency. Before the worldwide pharmaceutical conspiracy. The BERLIN-CHEMIE concern, which once created the drug, and its Russian subsidiary BERLIN-PHARMA CJSC refuse to comment on the situation, citing corporate secrets.
If you look from the other side, pharmacies have removed one of the many local anti-inflammatory drugs that are now in abundance on the shelf. Falimint cost about 200 rubles, even by the standards of 2017 - this is far from a cheap product.
"FALIMINT": reviews
I had a sore throat for a long time until the pharmacist at the pharmacy advised me to replace the drug, since the bacteria had developed, as she said, resistance to the drug. She recommended Falimint from Berlin-Chemie to us. The effect came quickly (although a slight cough remained), and the daughter also appreciated the effect of the product. The dragee has a minty or even more cooling taste.
Falimint really works. The effect will be especially noticeable if the sore throat is caused by inflammation due to a cold. After several resorptions of these tablets, the result becomes noticeable. Breathing immediately becomes easier and more pleasant. I don't think it will help with serious throat problems. For such cases, there are Dorithricin tablets containing an antibiotic, but I do not recommend self-medication - it is always better to consult a doctor for advice. Be always healthy!
I purchased the product and tried it out. Overall I liked it. Falimint relieves and soothes a sore throat quite well, tastes quite pleasant, and does not cause disgust. It is also worth noting the convenient packaging. It costs average, it cannot be called expensive. Quite effective, but I took several medications to treat my throat and cough, which does not underestimate the role of Falimint in improving my well-being.
Falimint also has side effects, but I didn’t feel any of those. Since the drug still has contraindications, it is better to consult a doctor before taking it. I wish you never to get sick, and if such a misfortune happens, do not engage in self-treatment! Consult doctors!