Skin damage and wounds are always unpleasant. What can we say about trophic ulcers - companions of severe varicose veins, which are characterized by very sluggish and slow healing due to impaired tissue nutrition. Solcoseryl can help heal such difficult lesions, as well as burns, frostbite, and eye damage.
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Composition and release form
Injection | 1 ml |
deproteinized dialysate from the blood of healthy dairy calves, standardized chemically and biologically (in terms of dry matter) | 42.5 mg |
excipients: water for injection - up to 1 ml |
in ampoules of 2 ml; there are 25 ampoules in a box; or in ampoules of 5 and 10 ml; There are 5 ampoules in a box.
Gel | 1 g |
deproteinized dialysate from the blood of healthy dairy calves, standardized chemically and biologically (in terms of dry matter) | 4.15 mg |
preservatives: methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) | |
excipients: calcium lactate; sodium carboxymethylcellulose; propylene glycol; water for injections |
in tubes of 20 g; 1 tube in a box.
Ointment | 1 g |
deproteinized dialysate from the blood of healthy dairy calves, standardized chemically and biologically (in terms of dry matter) | 2.07 mg |
preservatives: methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) | |
excipients: cetyl alcohol; cholesterol; white Vaseline; water for injections |
in tubes of 20 g; 1 tube in a box.
pharmachologic effect
Pharmacological action - antihypoxic, cytoprotective, regenerating, membrane stabilizing, angioprotective, wound healing.
The drug Solcoseryl is a deproteinized hemodialysate containing a wide range of low-molecular components of cell mass and blood serum of dairy calves with a molecular weight of 5000 D, the properties of which are currently only partially studied by chemical and pharmacological methods.
In in vitro tests, as well as during preclinical and clinical studies, it was found that Solcoseryl:
— increases reparative and regenerative processes;
— promotes activation of aerobic metabolic processes and oxidative phosphorylation;
— increases oxygen consumption in vitro and stimulates glucose transport into cells under hypoxic conditions and into metabolically depleted cells;
— increases collagen synthesis (in vitro);
— stimulates cell proliferation and migration (in vitro).
Solcoseryl gel does not contain fats as auxiliary components, making it easy to wash off. Promotes the formation of granulation tissue and the elimination of exudate.
From the moment fresh granulations appear and the wound dries, it is recommended to use Solcoseryl ointment, which contains fats as auxiliary components and forms a protective film on the wound surface.
Indications for the drug Solcoseryl
Solcoseryl solution for injection.
Occlusive diseases of peripheral arteries in stages III–IV according to Fontaine in patients with contraindications/intolerance to other medications;
chronic venous insufficiency, accompanied by trophic disorders (Ulcera cruris), in cases of their persistent course;
disorders of cerebral metabolism and blood circulation (ischemic and hemorrhagic stroke, traumatic brain injury).
Solcoseryl gel, ointment.
Minor damage (abrasions, scratches, cuts).
1st and 2nd degree burns (sunburn, thermal burns).
Frostbite.
Difficult-to-heal wounds (including trophic ulcers and bedsores).
What kind of medicine is Solcoseryl?
The drug has a beneficial effect on tissue metabolic processes. It improves tissue nutrition in case of damage, and also activates repair and regeneration processes.
Solcoseryl in injection form is used for extensive circulatory disorders (diseases of peripheral veins and arteries, strokes), ointment and jelly are used to treat ulcerative lesions and slow-healing wounds, and the gel is an ophthalmic agent. Thus, each of the release forms performs its own task of restoring damaged tissue.
The rate of absorption and distribution of the drug in the body, as well as the route of its elimination, cannot be determined by methods usual in pharmacology due to the characteristics of the active substance.
According to the results of a study of the drug on animals, the pharmacological effect develops within half an hour after the bolus injection. The therapeutic effect lasts for 3 hours.
Contraindications
Solcoseryl solution for injection.
Established hypersensitivity to calf blood dialysates;
since Solcoseryl injection contains derivatives of parahydroxybenzoic acid (E216 and E218), used as preservatives, as well as trace amounts of free benzoic acid (E210), the drug should not be used if there is an allergic reaction to the listed components;
There are no data on the safety of Solcoseryl injection in children, so the drug should not be prescribed to children under 18 years of age;
Solcoseryl injections should not be mixed when administered with other drugs, with the exception of isotonic sodium chloride solution and 5% glucose solution.
Solcoseryl gel, ointment.
Hypersensitivity to one of the components of the drug.
Use with caution if you are predisposed to allergic reactions.
Side effects
Solcoseryl solution for injection.
In rare cases, allergic reactions may develop (urticaria, hyperemia and swelling at the injection site, increased body temperature). In this case, it is necessary to stop using the drug and prescribe symptomatic treatment.
Solcoseryl gel, ointment.
In rare cases, allergic reactions in the form of urticaria and marginal dermatitis may develop at the site of application of Solcoseryl. In this case, you must stop using the drug and consult a doctor.
A short-term burning sensation may be observed at the site of application of Solcoseryl gel. If the burning sensation does not go away for a long time, the use of Solcoseryl gel should be abandoned.
Types of tattooing
Since permanent makeup has become very popular today, many types of lip and eyebrow tattooing have appeared. Let's look at them below.
Types of permanent lip makeup
Permanent lip makeup is achieved today through the use of various techniques. This:
- "Contouring" . In this case, the master applies pigment along the lip line. This method involves the artist using a tattoo machine and introducing a pigment that will match the natural color of the lips.
- "Contour with shading" . This method involves performing the contour first, and then the shading procedure. As a result, you will be able to obtain a well-defined natural beauty of the lips.
- "Easy watercolor" . This technique involves introducing soft pigment paints into the upper subcutaneous layer of the lips (to a depth of no more than 1 mm). Only after this is shading carried out.
- 3D technique . First, the master and the client select a pigment shade that matches the color of the salon visitor’s lips. After local anesthesia, a special mineral-based dye is injected. The second stage is a new procedure that involves shading the paint over the entire surface.
Types of eyebrow tattoo
Eyebrow tattooing comes in different forms. The type of tattoo depends on the chosen technique. Today in demand:
- the shot technique (also called the shading technique), the eyebrows end up looking like they have been tinted with shadow or shaded. This technique is suitable for those who do not want to radically change anything in their appearance. Shotting allows you to hide unevenness and neatly camouflage bald spots. The shot technique is also called the “ten-minute method.” Tattooing using this technique is done as follows: the artist visually divides the eyebrow into two equal parts, a bright dark pigment is injected subcutaneously into the center of the brow arch, gradually moving to each edge of the brow arch, the artist uses a coloring pigment of a lighter shade. This method allows your eyebrows to look beautiful and natural.
- Drawing technique. Its essence is that the master draws on the hairs, which become very similar to natural ones. This hair technique is divided into the Eastern method and the European method. The European technique is simpler, as it involves drawing hairs of the same length, one after another. Eastern technique involves drawing hairs of different lengths and at different angles. This type of eyebrow tattoo allows the brow ridges to look as natural as possible.
- 3D technology. This method involves a combination of shooting and the method of drawing hairs.
Interaction
Solcoseryl injections should not be mixed when administered with other medications, especially with phytoextracts.
The pharmaceutical incompatibility of Solcoseryl in the form of an injection solution with parenteral forms has been established:
Ginkgo biloba extract,
naftidrofuryl,
bencyclane fumarate.
As solutions for diluting Solcoseryl injection, only isotonic sodium chloride solution and 5% glucose solution should be used.
The interaction of Solcoseryl with other topical medications has not been established.
Directions for use and doses
Solcoseryl injection solution: intravenous or intramuscular.
In the treatment of occlusive diseases of peripheral arteries in stages III–IV according to Fontaine - 20 ml intravenously daily. Intravenous drip administration in isotonic sodium chloride solution or 5% glucose solution is possible. The duration of therapy is up to 4 weeks and is determined by the clinical picture of the disease.
In the treatment of chronic venous insufficiency accompanied by trophic disorders (Ulcera cruris) - 10 ml intravenously 3 times a week. The duration of therapy is no more than 4 weeks and is determined by the clinical picture of the disease. An important additional measure aimed at preventing peripheral “venous” edema is the application of a pressure bandage using an elastic bandage.
In the presence of local trophic tissue disorders, simultaneous therapy with Solcoseryl jelly and then Solcoseryl ointment is recommended.
In the treatment of ischemic and hemorrhagic strokes in severe and extremely severe forms, the main course is 10 or 20 ml intravenously, respectively, daily for 10 days. Upon completion of the main course - 2 ml intramuscularly or intravenously for 30 days.
Traumatic brain injury (severe brain contusion) - 1000 mg intravenously, daily for 5 days.
If intravenous administration of the drug is not possible, the drug can be administered intramuscularly, usually 2 ml per day undiluted.
When using the undiluted drug intravenously, it must be administered slowly, since it is a hypertonic solution.
Solcoseryl gel, ointment: topically.
Apply directly to the wound surface after preliminary cleansing of the wound using a disinfectant solution.
Before starting treatment of trophic ulcers, as well as in cases of purulent infection of the wound, preliminary surgical treatment is necessary.
Solcoseryl gel is applied to fresh wounds, wounds with wet discharge, and to ulcers with signs of weeping - a thin layer on a cleaned wound 2-3 times a day. It is recommended to lubricate areas where epithelization has begun with Solcoseryl ointment. The use of Solcoseryl gel continues until pronounced granulation tissue forms on the damaged skin surface and the wound dries out.
Solcoseryl ointment is used primarily for the treatment of dry (non-wetting) wounds.
Solcoseryl ointment is applied in a thin layer to a cleaned wound 1-2 times a day; it can be used under bandages. The course of treatment with Solcoseryl ointment continues until the wound is completely healed, its epithelization and the formation of elastic scar tissue.
For the treatment of severe trophic damage to the skin and soft tissues, the simultaneous use of parenteral forms of Solcoseryl is recommended.
What is tattooing?
Tattooing refers to permanent makeup, which is applied according to a principle similar to a tattoo. But tattooing, unlike tattoos, disappears over time. This metamorphosis is explained by the fact that a dye is introduced under the human skin to a depth of no more than 1 mm. The most popular tattooing today is eyebrow tattooing, as well as lip tattooing. We will devote this article to their description.
What is lip tattoo
Lip tattooing involves changing the lip line by drawing it more clearly. Lip tattooing allows you not only to change the contour, but also to make it more correct. Permanent lip makeup allows you to give up the daily application of lipstick and pencil to your lips.
What is eyebrow tattooing
Eyebrow tattooing is a popular service among ladies, which allows you not only to add richness to your eyebrows, but also to change their shape. Eyebrow tattooing frees the fair sex from the daily task of drawing in eyebrows with a pencil.
special instructions
Solcoseryl (gel, ointment) should not be applied to a contaminated wound, since it does not contain antimicrobial components.
The use of Solcoseryl, like all other medications, is undesirable during pregnancy and breastfeeding and is possible only when absolutely necessary and under the supervision of a doctor.
If you experience pain, redness of the skin near the site where Solcoseryl was applied, secretion from the wound, or increased body temperature, you should immediately consult a doctor.
If, when using Solcoseryl, healing of the affected area is not observed within 2-3 weeks, you should consult a doctor.
What is the best way to treat herpes: effective ointments and tablets for herpes infection
The most well-known antiherpetic drug is acyclovir. Its effectiveness for the treatment of types 1, 2, 3 and 4 of herpes has been proven in clinical studies. Acyclovir is recommended by the World Health Organization to combat HSV.
Acyclovir stops the reproduction of the pathogen and inhibits its activity. It is mainly used in the form of a cream, which is applied several times a day to the affected area of the skin. This drug also exists in tablet form. The rules of admission in each individual case should be discussed with the attending physician.
The drug Penciclovir is considered no less effective. It is also recommended by WHO, as this medication has successfully passed numerous clinical trials. It suppresses the activity of herpes virus types 1 and 2, and is also effective against its strains. Penciclovir can be used in patients who are resistant to acyclovir.
However, Valaciclovir is considered the most effective drug against herpes infection. It is more effective than the previous two medications. In the human body, under the influence of enzymes, valacyclovir is converted into acyclovir.
In almost all antiherpetic drugs, the main active ingredient is acyclovir, penciclovir or valacyclovir.
Drugs for the treatment of oral herpes
There are a wide variety of antiviral medications to treat the symptoms of this disease, which are available in dosage forms for topical use. They begin to act faster than drugs in tablet forms and act directly on the site of infection.
The best creams and ointments for type 1 herpes:
- Pen-Gerpevir;
- Atsik;
- Lipster;
- Gerpevir;
- Zovirax;
- Acyclostad;
- Agerp.
Acyclovir, penciclovir and valacyclovir are also included in medications that must be taken orally, that is, through the mouth.
They are included in the following herpes tablets:
- Gropivirine;
- Valavir;
- Acyclovir-Darnitsa;
- Atsik;
- Lipster.
Drugs for the treatment of genital herpes
Some of the medications listed above are suitable to combat it, but medical experts advise using drugs that contain valacyclovir. This is due to the fact that HSV type 2 has a greater number of negative symptoms and can cause complications, and valacyclovir is stronger than penciclovir and acyclovir.
Effective drugs to combat HSV type 2:
- Proteflazid drops, Proteflazid suppositories;
- Valavir tablets;
- Roller tablets;
- Lipster tablets;
- Valaciclovir-Hetero tablets.
In addition, to treat the viral infection in question, the following auxiliary agents are used:
1. Immunomodulators . They help strengthen the immune system and enhance protective responses against viruses.
Examples of these tools:
- Cycloferon;
- Anaferon.
2. Antiseptics . They are used to prevent re-infections. Antiseptics are used to treat infection sites.
The most famous medicines:
- Chlorhexedine;
- Miramistin.
3. Non-steroidal anti-inflammatory drugs (NSAIDs) . Herpes infection is accompanied by inflammatory processes that help suppress NSAIDs.
Examples of these drugs:
- Ibuprofen;
- Nimesil.
4. Analgesics-antipyretics . With genital herpes, fever may occur. It can be brought down with the help of the most famous analgesic-antipyretic paracetamol.
5. Antihistamines . During HSV, a person experiences itching sensations at the sites of infection. Ulcers and blisters are very itchy, but they should never be scratched, otherwise scars will remain in their place. Antihistamines are used to reduce itching.
Popular products of this group.
- Erius;
- Claritin;
- Eden.
The doctor must decide which remedy to choose for the treatment of herpes simplex virus and which auxiliary medications to take in each individual case. And to prevent the occurrence of the disease or its relapse, you can carry out simple prevention.