Comparison of the effectiveness of Kamistad and Dentinox
Dentinox is more effective than Kamistad - this means that the ability of the drug substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Dentinox is more pronounced, then with Kamistad it is impossible to achieve this effect even in large doses.
Also, the speed of therapy is an indicator of the speed of the therapeutic action; Dentinox and Kamistad are also different, as is the bioavailability - the amount of the drug reaching the place of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Similarities and differences between the two drugs
At first glance, it may seem that Kalgel and Kamistad Baby are the same product under different brands. They have a number of similar characteristics:
- Same appearance and packaging.
- They are used in the same cases.
- Same mechanism of action.
- Same method of application.
Nevertheless, there are still differences. First of all, you should pay attention to the following parameters.
Compound
There is an opinion that polidocanol is a derivative of lidocaine. This is wrong. Polidocanol has a weak anesthetic effect , but it has nothing to do with lidocaine. It acts only on surface receptors, without involving the nerve channel. Therefore, the drug does not have a pronounced effect. Kamistad Baby is recommended to be used at night. While the medicine is working, the child will have time to fall asleep.
In addition to pain relief, thanks to the anti-inflammatory effect of chamomile extract, Kamistad Baby is prescribed for inflammatory processes in the oral cavity in children .
Lidocaine, which is part of Kalgel, affects the entire depth of the nerve canal. Therefore, the effect of Kalgel is stronger and longer than Kamistad Baby. Cetylpyridinium chloride has a disinfecting effect . But long-term use of this substance is not advisable, as it can disrupt the normal microflora of the mouth and cause stomatitis.
Despite its weak effect, polidocanol remains on the oral mucosa longer . Thus, Kalgel acts stronger, and Kamistad Baby lasts longer. Both remedies do not solve the problem as a whole; they provide only symptomatic treatment.
Overdose
Often, when trying to apply the gel, mothers are faced with the fact that the child licks the gel off his finger . In these cases, a drug overdose may occur. Kamistad Baby consists of 50% natural products ; during the observation period, no cases of complications due to overdose were identified.
Kalgel is 100% chemical substances . Kalgel contains lidocaine, which is a strong allergen.
An overdose of this drug can cause respiratory depression in a child . In addition, lidocaine has an effect on the heart muscle and reduces the heart rate. In 2014, US medical services strongly recommended the abandonment of lidocaine gels due to increased complications in infants. Therefore, when using Kalgel you need to be careful not to exceed the permitted dosage.
Child's age
The instructions for Kamistad Baby indicate that the product can be used in children from 3 months . In practice, the medicine is successfully used from the birth of a child.
Kalgel is used no earlier than 5 months . This is due to the increased allergenicity of the drug. In addition, the product has a number of contraindications.
Comparison of safety of Kamistad and Dentinox
The safety of a drug includes many factors.
At the same time, it is higher for Kamistad than for Dentinox. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Kamistad, as well as in Dentinox, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Kamistad has fewer risks when used than Dentinox.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Kamistad and Dentinox.
Kalgel
Produced in Poland by GlaxoSmithKline Pharmaceuticals. Release form, also in tubes of 10 grams. Yellowish-brown color, menthol smell. Used for teething in children from five months.
Contains:
- Lidocaine.
- Cetylpyridinium chloride.
- Excipients, sorbitol, alcohol, sweeteners.
Lidocaine has a local anesthetic effect . Cetylpyridinium chloride is an antiseptic and prevents the proliferation of bacteria and fungi in the oral cavity.
Method of use: the drug in an amount of 5-7 mm is lightly rubbed into the inflamed gum. It begins to act within a few minutes. Repeated application no earlier than 20 minutes, no more than 6 times a day.
There are contraindications:
- Hypersensitivity to components.
- Severe diseases of the kidneys, liver, heart.
- Low pressure.
- Bradycardia.
May cause allergic reactions . If signs of an allergy appear, you should consult a doctor immediately.
Comparison of addiction between Kamistad and Dentinox
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “o syndrome” in Kamistad is quite similar to the similar values in Dentinox. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Kamistad the meaning of the “syndrome” is quite small, however, the same as in Dentinox.
Kamistad Baby
Manufacturer: German pharmaceutical company STADA Arzneimittel AG . Available in tubes of 10 g . Shelf life : 2.5 years . Minty taste and smell with notes of chamomile and honey. Transparent gel with a yellowish-brown tint. According to the instructions, it is used for pain and discomfort from teething in children from 3 months.
Includes:
- Polidocanol.
- Chamomile extract.
- Excipients, including glycerin, flavorings, sweeteners.
Polidocanol is a weak anesthetic . Has a cooling and distracting effect. Chamomile extract helps reduce inflammation and swelling of the gums and oral mucosa.
Directions for use: a pea-sized amount of product is lightly rubbed into the painful area of the gum. Pain relief occurs within a few minutes. The only contraindications are individual intolerance. No side effects
Comparison of side effects of Kamistad and Dentinox
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Kamistad's rate of adverse events is almost the same as Dentinox's. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Kamistad are similar to Dentinox: how quickly the body recovers after taking it and whether it recovers at all.
INSTRUCTIONS FOR USE
If teething is not accompanied by inflammation of the oral mucosa, then both drugs can be used. They exhibit pronounced analgesic and distracting activity. After applying dental gels, their ingredients do not penetrate into the bloodstream. Therefore, the development of systemic side effects is completely excluded.
INDICATIONS AND CONTRAINDICATIONS
The drug Kalgel is aimed at use in pediatrics, therefore it contains more flavorings and flavoring additives. Cholisal is used not only for teething. It is included in therapeutic regimens for diagnosing periodontitis, gingivitis, and stomatitis. It is used for any inflammatory diseases of the oral mucosa in adults. What is better for stomatitis - Cholisal or Kalgel:
- both drugs disinfect the mucous membranes of the oral cavity;
- Cholisal is more active against pathogenic microorganisms.
Dental gels are good at eliminating both fungal and bacterial infections. Contraindications to their use are hypersensitivity to the ingredients.
Dentists prescribe Kalgel to children from 5 months. One of the contraindications for Cholisal is age under 12 months. It is not used in the treatment of pregnant women, since its safety has not been confirmed by clinical trials. The drug is not prescribed to patients with severe heart, liver and kidney diseases, arterial hypotension.
SIDE EFFECTS
But doctors recommend not using Cholisal in the treatment of children under 3 years of age due to the provocation of excess salivation.
When treated with dental products, a burning and tingling sensation sometimes occurs. It disappears after 3-5 minutes. In rare cases, an allergic reaction develops - swelling and a small rash.
METHOD OF APPLICATION AND DOSES
The ingredients included in dental products ensure rapid absorption of active substances. The gels are securely held on the gums and do not enter the stomach when swallowing saliva. A single dose is approximately 0.5 cm of a strip of product squeezed out of the tube.
For pain relief, it is enough to apply the drug to the gums 3-4 times a day, lightly rubbing. You should first remove the resulting plaque with a sterile cloth. The duration of treatment with Cholisal and Kalgel is determined by the doctor, taking into account the speed of teething and the number of teeth.
Comparison of the effectiveness of Kalgeli and Dentinox
The effectiveness of Kalgeli is quite similar to Dentinox - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Kalgeli is more pronounced, then using Dentinox even in large doses will not achieve this effect.
Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Kalgeli and Dentinox. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.
