To treat inflammatory diseases of the oral cavity, it is recommended to use effective means, for example, the inexpensive Metrogyl Denta gel. It is used for the prevention and treatment of gingivitis, stomatitis, periodontal disease and other dangerous pathologies. The drug is characterized by rapid action and minimal likelihood of side effects. Sold in pharmacies without a doctor's prescription.
Gel "Metrogil Denta": description, composition
The drug is available in the form of a gel, which is packaged in plastic tubes of various sizes. The active ingredients are chlorhexidine and metronidazole.
It has high antimicrobial activity due to the presence of 2 substances in its composition. The following additional compounds are used: propylene glycol, water, sodium in the form of hydroxide, others.
The product is stored under normal room conditions at temperatures up to 25 degrees Celsius. It is important to protect from direct sunlight and prevent children from accessing it. The shelf life of the gel is 3 years from the date of production. After this time, the drug cannot be used.
Metrogyl gel is a reliable product in dentistry
Metrogyl Denta is a dental medicinal product produced by pharmaceutical companies in the form of a gel. Thanks to the combined composition, including:
- antibiotic;
- antiseptic,
- the medicine has a wide spectrum of antimicrobial action and is recommended by experts for use by both adults and children over 6 years of age.
The main active ingredients of the drug are metronidazole and chlorhexidine.
Metronidazole, known for its antimicrobial properties, is successfully used in medicine for:
- peptic ulcers;
- chronic colitis;
- inflammation of the urinary system;
- genital infections,
- as well as for the purpose of preventing complications that often arise after surgery.
Chlorhexidine is an effective antiseptic used in medical practice:
- during preoperative treatment of hands;
- when cleaning medical premises;
- for disinfection of instruments.
Thanks to its gel consistency, Metrogyl is successfully used in dentistry, but in addition, the product can help solve some cosmetic problems and stop the inflammatory processes of the external genitalia.
Metrogil:
instructions for use
In dental practice, the drug is used to treat:
- gingivitis;
- periodontitis;
- bacterial stomatitis;
- lip inflammation;
- inflammatory processes of the hoods over wisdom teeth;
- inflammation of the mucous membrane;
- alviolite of the socket of an extracted tooth,
- It is also used as an additional agent in the treatment of periodontitis and periodontal abscess.
However, despite the effectiveness of Metrogyl, the instructions of which recommend its use for these diseases, an experienced doctor may prescribe other drugs, depending on the individual characteristics of the patient’s body and the complexity of the case.
Metrogyl denta goes on sale in laminated plastic tubes of 20 grams and is sold without a prescription.
Metrogyl, reviews of which from experts allow us to recommend to patients a relatively inexpensive and effective antiseptic drug, is often used as an everyday means of oral hygiene, which helps prevent many inflammatory processes.
Pharmacodynamics
The drug has a combined effect, since it contains 2 active components with an antibacterial effect:
- Chlorhexidine acts on a wide class of gram-negative and gram-positive bacteria. At the same time, it does not inhibit the vital activity of beneficial lactobacilli.
- Metronidazole destroys bacteria that live in an oxygen environment, i.e. aerobic microorganisms. They are the ones that cause periodontal disease.
The gel is used topically, so its active components are practically not absorbed through the walls of blood vessels and do not enter the bloodstream.
Application benefits
Despite the rather low concentration of active substances and the lack of analgesic effect, Metrogyl Denta gel has a number of advantages over more modern drugs used in medicine, for example:
- the drug is perfectly fixed on the mucous membranes;
- has a fairly high efficiency,
- In addition, its affordable cost allows you to regularly use this product for preventive purposes.
The active components of the drug allow you to influence pathogenic microorganisms, but are not able to block mediators of inflammatory processes in tissues, therefore, in the treatment of many diseases, experts recommend combined procedures to achieve a more effective result.
Indications for use
The drug is used for various inflammatory pathologies occurring in the oral cavity:
- gingivitis in the acute and chronic stages;
- Vincent's gingivitis in acute form;
- periodontitis in acute and chronic form;
- aphthous stomatitis;
- juvenile prodontitis;
- periodontal disease as a complication of gingivitis;
- cheilitis;
- inflammation of the oral mucosa as a complication after using a prosthesis;
- alveolitis of post-extraction type;
- periodontitis, abscess.
Note!
The description of the drug Metronidazole denta gel for gums tube 20g on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
Contraindications and side effects
In some cases the gel cannot be used:
- individual sensitivity to any component of the drug;
- blood diseases, including in the past observation;
- pathologies of the central and peripheral nervous system;
- children up to 17 years old inclusive.
During pregnancy and lactation, the use of the gel is allowed with caution. A preliminary consultation with a doctor is recommended. Admission is carried out only if the expected benefit is greater than the potential risks.
When taking the drug, skin rashes, itching, headaches, redness, hives and other allergic reactions are possible. In this case, it is recommended to stop treatment and consult a specialist for advice. You may need to change the drug.
Features of use
The use of Metrogil Dent gel, especially in the initial stages of treatment, can cause bleeding gums, increased swelling and burning. Such symptoms may appear within a few days, but if they continue, you should stop using the drug.
Despite the fact that no obvious contraindications or side effects have been identified for the drug, Metrogyl is not recommended for use for the treatment of:
- children under 6 years of age;
- women in the first trimester of pregnancy,
- In addition, it is not advisable to use the drug while breastfeeding and, if it is necessary to use it, you will have to stop breastfeeding.
Many experts recommend avoiding drinking alcohol during treatment with Metrogyl gel, since it contains an antibiotic that can be absorbed into the blood, even when applying applications.
In addition, the use of the drug should be discontinued at the first signs of intolerance to the drug.
Studies have shown a negative effect of the drug when taken together with anticoagulants, since the active substances of Metrogyl can enhance their effect, which can cause bleeding.
Experts recommend careful use of the drug, since, for example, swallowing the gel can have serious consequences:
- nausea;
- dizziness,
- which is facilitated by metronidazope, which is part of the product.
Instructions for use of gel "Metrogil Denta"
The drug is used only locally, without oral administration. The instructions depend on the indications:
- In case of inflammation, the gel is applied to the surface of the gums in a small layer. This can be done with a clean finger or a sterile cotton swab. The procedure is repeated 2 times a day. The medicine cannot be washed off, so you should avoid contact with water, food and drinks for half an hour after taking it. Therapy is continued for 7-10 days.
- To treat periodontitis, the affected surfaces must be treated with a gel application. This can be done in a clinic or on your own. The layer needs to be applied for 30 minutes. The procedures are carried out several times until complete recovery. As a rule, 2 times a day for 7-10 days is enough.
- In the case of aphthous stomatitis, the affected areas of the mucous membranes are coated with the composition 2 times a day for 7-10 days.
- To prevent chronic gingivitis, the gel should be used in the same way - it is applied to the gums 2 times a day, treatment is continued for 1 to 1.5 weeks. The same cycles are repeated 2-3 times a year.
- To prevent post-extraction type alveolitis, the cavity after the extracted tooth is coated with gel 2 or 3 times a day for 1-1.5 weeks.
Pharmacological properties of the drug Metrogyl vaginal gel
Metrogyl vaginal gel (metronidazole; 1-(β-oxyethyl)-2-methyl-5-nitroimidazole) is an antiprotozoal and antibacterial agent for vaginal use. Highly active against anaerobic bacteria (bacteroides, fusobacteria, clostridia, anaerobic cocci) and protozoa ( Trichomonas vaginalis, Entamoeba histolytica, Lamblia ). Active against most strains of microorganisms that cause bacterial vaginosis: Gardnerella vaginalis, Bacteroides spp., Mobiluncus spp., Peptostreptococcus spp. Aerobic microorganisms are insensitive to metronidazole. The mechanism of action is due to the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microbial cells, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria. After a single vaginal injection of 5 g of vaginal gel, the average maximum concentration of metronidazole in the blood serum of healthy women reaches 237 ng/ml, which is 2% of the average maximum concentration of metronidazole (12.785 ng/ml) when taken orally at a dose of 500 mg. The time to reach maximum concentration is 6–12 hours after a single vaginal injection of 5 g of gel and 1–3 hours after oral administration of metronidazole at a dose of 500 mg. The relative bioavailability of metronidazole in the form of a vaginal gel is 2 times higher than the bioavailability of metronidazole in the form of vaginal tablets (500 mg), which is due to the high penetrating ability of the drug. Therefore, the therapeutic effect of the vaginal gel is achieved at a lower concentration of metronidazole. A lower dose of vaginal gel results in lower serum metronidazole concentrations, which is accompanied by a much lower incidence of side effects.
special instructions
The drug has an antiseptic effect and disinfects the oral cavity well. However, its use does not replace the need to brush your teeth, which should be done as usual 2 times a day - in the morning and before bed.
If the gel is accidentally ingested (can be swallowed by a child), you should immediately seek emergency help. You may need gastric lavage and appropriate medications.
After the expiration date, the remaining product should not be thrown into the sewer or as garbage on the street. It is placed in a tight bag and then thrown into a trash container.
There is no data on the effect of the gel on the speed of psychomotor reactions. Therefore, it can be used by drivers and other workers whose activities involve the need to make quick decisions.
Drug interactions Metrogyl vaginal gel
When using Metrogyl vaginal gel topically, the interaction with other drugs is insignificant, however, when administered simultaneously with certain drugs, caution should be exercised: metronidazole enhances the effect of indirect anticoagulants, leading to an increase in prothrombin time; simultaneous use with disulfiram can lead to the development of neurological symptoms, so Metrogyl should not be prescribed to patients who have taken disulfiram over the past 2 weeks; Cimetidine inhibits the metabolism of metronidazole, which may lead to an increase in its concentration in the blood serum and an increased risk of side effects.
